Truth of ART procedure

In the seventies (1978), after several attempt the first test-tube baby was born. Doctors starts removing eggs from the women having problem in conceiving and start fertilizing it in laboratories. This whole procedure is later named as In Vitro Fertilization (IVF). Assisted Reproductive Technology (ART) refers to the treatments that include the handling the biological process outside to the body. ART procedures accounts 22 percent result in baby's birth.

Age is the most important factor that have serious impact on infertility. It affects the success rates of infertility treatment and ability to conceive naturally. At the age of 30 if a women have 20% chance to conceive then at 40 it will be reduced to 5%. Women older than 40 years, If having failed attempt to conceive then, immediately consult with the fertility specialist. For those who were older and having a regular failed attempts of pregnancy can opt for ART procedures. Whenever a couple feels ready to conceive naturally but age damaged their fertility. Then, ART procedures comes as to rescue.

Some of common assisted reproductive technology are:-

1) IVF( In Vitro Fertilization) - It is procedure in which women is given high doses of injection to multiple follicle of egg. IVF procedure involves :-

a) Ovarian hyperstimulation with the injection medication.
b) Transvaginal ultrasound and bloodwork monitoring.
c) Maturation injection
d) Oocyte retrieval
e) Fertilization

When is IVF used?
a) Male infertility
b) Tubal infertility
c) Unexplained infertility
d) Fertilization failure
e) Preimplantation genetic diagnosis or screening
f) Poor ovarian reserve
g) Older female age
h) Polycystic ovarian syndrome 
i) Endometriosis

How IVF improves pregnancy rate?

A) Multiple egg production.
B) Bypasses issues with fertilization.
C) Optimal embryo selection.

2) ICSI (Intracytoplasmic sperm injection)
- It is a procedure in which sperm is injected into egg and fertilization occurs. Then resulting embryos get transferred to uterus after 2-3 days. The whole procedure takes place in laboratory.

When ICSI is used?

A) Male infertility.
B) Donor sperm.
C) Fertilization failure.
D) Pre implantation genetic diagnosis or screening.
E) Unexplained Infertility.

3) Egg donation - Egg quality have a very important role for women getting pregnant. As the age passes egg quality diminishes. IVF can also be done with donated eggs of another women. Sperm is injected in donor's egg which results embryo and it get transferred in uterus.

GIFT (Gamete intrafallopian transfer) - This is a procedure in which sperm is injected into egg and the with the help of small incision in abdomen, the mixture is inserted into fallopian tube and embryo get implants inside.

ZIFT (Zygote intrafallopian transfer) - This is a procedure in which sperm is injected in eggs and fertilization occurs. The resulting embryo is transferred in fallopian tube through small incision on abdomen.